Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 6/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25262809 | 0.85 | WNT3A (0.39) | WNT3ACDK9CCNT1GRM5GRM1 | |
| SCHEMBL30499641 | 0.85 | WNT3A (0.39) | WNT3ACDK9CCNT1GRM5GRM1 | |
| SCHEMBL25869400 | 0.83 | USP30 (0.34) | ACVR1BTGFBR1ACVRL1 | |
| SCHEMBL25869388 | 0.82 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL25130973 | 0.81 | TGFBR1 (0.38) | JAK1TGFBR1ACVRL1 | |
| SCHEMBL25130851 | 0.80 | TGFBR1 (0.38) | JAK1ACVR1BTGFBR1ACVRL1 | |
| SCHEMBL25131855 | 0.80 | TGFBR1 (0.38) | JAK1TGFBR1ACVRL1 | |
| SCHEMBL30499647 | 0.79 | LMNA (0.40) | WNT3ACDK9CCNT1TGFBR1 | |
| SCHEMBL25307609 | 0.79 | LMNA (0.40) | WNT3ACDK9CCNT1TGFBR1 | |
| SCHEMBL25131836 | 0.79 | TGFBR1 (0.35) | ACVR1BTGFBR1ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135107-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-07-20 | — | — | WO | disclosed |