SCHEMBL2586982

SCHEMBL2586982

CCOC(C)COC(=O)CS

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPT P10636 1/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
LMNA P02545 3/20 0.32
ALDH1A1 P00352 4/20 0.31
TRPA1 O75762 1/20 0.31
CYP3A4 P08684 1/20 0.30
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4983415 0.85 MAPT (0.40) TSHRMAPTMGAMGAASI
SCHEMBL445901 0.83 NAAA (0.38) TSHRHSD17B10MAPTMGAMGAA
SCHEMBL99109 0.81 TSHR (0.35) TSHRHSD17B10
SCHEMBL98954 0.81 TSHR (0.35) TSHRHSD17B10
SCHEMBL2136463 0.81
SCHEMBL16389873 0.81 TSHR (0.46) TSHRHSD17B10MAPTGAAALDH1A1
SCHEMBL9936248 0.80 MAPT (0.34) TSHRHSD17B10MAPTMGAMGAA
SCHEMBL2700961 0.80 NAAA (0.35) TSHRHSD17B10MAPTMGAMGAA
SCHEMBL27646329 0.80 MAPT (0.46) TSHRMAPTLMNAALDH1A1CYP3A4
SCHEMBL99241 0.79 TSHR (0.41) TSHRHSD17B10MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9642783-B2 Depilatory compositions L'OREAL (FR) 2017-05-09 US claimed
WO-2015149975-A1 DEPILATORY COMPOSITIONS L'OREAL (FR) 2015-10-08 WO claimed
US-20150283042-A1 DEPILATORY COMPOSITIONS L'OREAL (FR) 2015-10-08 US claimed
US-9642783-B2 Depilatory compositions L'OREAL (FR) 2017-05-09 US disclosed
WO-2015149975-A1 DEPILATORY COMPOSITIONS L'OREAL (FR) 2015-10-08 WO disclosed
US-20150283042-A1 DEPILATORY COMPOSITIONS L'OREAL (FR) 2015-10-08 US disclosed
US-20130202544-A1 THICKENED COMPOSITONS OF HIGH PH ISP INVESTMENTS INC. (US) 2013-08-08 US disclosed
WO-2011137321-A1 THICKENED COMPOSITONS OF HIGH PH ISP INVESTMENTS INC. (US) 2011-11-03 WO disclosed
US-20080131389-A1 Hair Relaxer SHOWA DENKO K.K. (JP) 2008-06-05 US disclosed
EP-1845940-A1 HAIR RELAXER Showa Denko K.K. (JP) 2007-10-24 EP disclosed
WO-2006083031-A1 HAIR RELAXER SHOWA DENKO K.K. (JP) 2006-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080131389-A1 Hair Relaxer BHMT2, BHMT, MGMT TSHR 1342/4885HSD17B10 471/4885MAPT 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.