Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19240735 | 0.83 | EPHX2 (0.60) | EPHX2EPHX1 | |
| SCHEMBL15998851 | 0.79 | ALDH1A1 (0.47) | EPHX2ALDH1A1 | |
| SCHEMBL25876410 | 0.76 | ITGB3 (0.41) | EPHX2EPHX1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL21480105 | 0.76 | ALDH1A1 (0.45) | EPHX2ALDH1A1 | |
| SCHEMBL24932886 | 0.75 | KCNH2 (0.41) | ITGB3ITGA2B | |
| SCHEMBL23572075 | 0.75 | TSHR (0.35) | EPHX2EPHX1ITGB3ITGA2B | |
| SCHEMBL25870846 | 0.74 | CYP1A2 (0.44) | EPHX2ALDH1A1 | |
| SCHEMBL25525838 | 0.74 | EPHX2 (0.40) | EPHX2EPHX1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL25876613 | 0.74 | ALDH1A1 (0.49) | EPHX2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL22306153 | 0.73 | EPHX2 (0.40) | EPHX2EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |