Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765702 | 0.75 | OPRM1 (0.53) | OPRM1OPRL1ALDH1A1 | |
| SCHEMBL15998890 | 0.74 | OPRM1 (0.51) | OPRM1OPRL1ALDH1A1 | |
| SCHEMBL25870355 | 0.73 | EPHX2 (0.44) | EPHX2EPHX1ALDH1A1 | |
| SCHEMBL25090026 | 0.72 | HRH3 (0.35) | OPRM1OPRL1 | |
| SCHEMBL24941825 | 0.71 | KDM4E (0.37) | EPHX2EPHX1CHRM1OPRM1OPRL1 | |
| SCHEMBL13131126 | 0.71 | HSD11B1 (0.51) | OPRM1OPRL1ALDH1A1 | |
| SCHEMBL25703446 | 0.70 | ALDH1A1 (0.53) | EPHX2EPHX1CHRM4CHRM1OPRM1 | |
| SCHEMBL16835485 | 0.70 | CYP2C19 (0.32) | EPHX2CHRM4CHRM1OPRM1OPRL1 | |
| SCHEMBL18256166 | 0.70 | OPRM1 (0.42) | CHRM4CHRM1OPRM1OPRL1ALDH1A1 | |
| SCHEMBL21765703 | 0.70 | OPRM1 (0.47) | OPRM1OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160192-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |