Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 3/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2594071 | 0.80 | SCD (0.37) | METTLR9TLR7SCDKHK | |
| SCHEMBL16015962 | 0.70 | SIGMAR1 (0.37) | HTR2CSIGMAR1METTLR9TLR7 | |
| SCHEMBL2583777 | 0.68 | GPR119 (0.41) | — | |
| SCHEMBL4789465 | 0.68 | HTR2C (0.66) | HTR2CSIGMAR1KHK | |
| SCHEMBL7394377 | 0.67 | HTR2C (0.60) | HTR2CSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9532611 | 0.67 | HTR2C (0.67) | HTR2CSIGMAR1KHK | |
| SCHEMBL11524342 | 0.66 | HTR2C (0.56) | HTR2CSIGMAR1TLR9TLR7INPPL1 | |
| SCHEMBL2590930 | 0.66 | HTR2C (0.47) | HTR2CSCDSCN9A | |
| SCHEMBL13128831 | 0.66 | SCD (0.38) | SIGMAR1SCD | |
| Hydrochloric Acid SCHEMBL4789235 | 0.66 | HTR2C (0.61) | HTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566860-A1 | BICYCLIC HETEROARYL COMPOUNDS AS GPR119 MODULATORS | Bristol-Myers Squibb Company (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140160-A1 | BICYCLIC HETEROARYL COMPOUNDS AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-11-10 | — | — | WO | disclosed |