SCHEMBL10134166

SCHEMBL10134166

O=C1C(=Cc2ccc(N(c3ccccc3)c3cccs3)cc2)C(=O)c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
ALDH1A1 P00352 4/20 0.50
HPGD P15428 4/20 0.50
HTT P42858 1/20 0.50
LCK P06239 2/20 0.41
MIF P14174 1/20 0.41
MEN1 O00255 4/20 0.40
MAPT P10636 4/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
POLB P06746 2/20 0.40
THRB P10828 2/20 0.40
PKM P14618 2/20 0.40
MAPK1 P28482 2/20 0.40
MDM2 Q00987 2/20 0.40
GAA P10253 1/20 0.40
TNNI3 P19429 1/20 0.40
TNNT2 P45379 1/20 0.40
TNNC1 P63316 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10134160 0.94 KMT2A (0.53) KMT2AALDH1A1HPGDHTTLCK
SCHEMBL10134179 0.90 KMT2A (0.40) KMT2AALDH1A1HPGDHTTLCK
SCHEMBL10134171 0.84 KMT2A (0.41) KMT2AALDH1A1HPGDHTTLCK
SCHEMBL2716738 0.84 LCK (0.51) KMT2AALDH1A1HPGDLCKMIF
SCHEMBL10134163 0.83 ALDH1A1 (0.42) KMT2AALDH1A1HPGDHTTLCK
SCHEMBL12761795 0.83 KMT2A (0.44) KMT2AALDH1A1HPGDHTTLCK
SCHEMBL18913100 0.81 ALDH1A1 (0.54) KMT2AALDH1A1HPGDHTTMEN1
SCHEMBL34474804 0.80 LCK (0.47) KMT2AALDH1A1HPGDLCKMIF
SCHEMBL25870773 0.79 ALDH1A1 (0.45) KMT2AALDH1A1HPGDHTTMEN1
SCHEMBL10134162 0.79 ALDH1A1 (0.45) KMT2AALDH1A1HPGDHTTLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2439803-B1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD FOR PRODUCING SAME, PHOTOSENSOR, IMAGING ELEMENT AND METHOD OF DRIVING SAME FUJIFILM CORP (JP) 2017-11-08 EP disclosed
US-9349965-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, method for preparing photoelectric conversion device, method for using photoelectric conversion device, photosensor and imaging device FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847208-B2 Photoelectric conversion device and imaging device having decreased dark current FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847208-B2 Photoelectric conversion device and imaging device having decreased dark current FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8378339-B2 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8338691-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2012-12-25 US disclosed
US-8258506-B2 Photoelectric conversion device, production method thereof and imaging device FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
EP-2306541-A1 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods Fujifilm Corporation (JP) 2011-04-06 EP disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308372-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20090223566-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX KMT2A 2433/4885ALDH1A1 1609/4885HPGD 2003/4885
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO KMT2A 2284/4885ALDH1A1 1665/4885HPGD 1848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.