Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652252 | 0.84 | SMN1; SMN2 (0.48) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL21782835 | 0.81 | PKM (0.52) | MAPTALDH1A1LMNATP53RXFP1 | |
| SCHEMBL23367905 | 0.81 | RECQL (0.48) | MAPTALDH1A1SMN1; SMN2TRPA1ITGB1 | |
| SCHEMBL13753076 | 0.77 | CNR2 (0.48) | ALDH1A1POLBMAPK1TRPA1CYP1A2 | |
| SCHEMBL14236256 | 0.75 | GAA (0.49) | LMNAMEN1KMT2ATRPA1CYP1A2 | |
| SCHEMBL19524976 | 0.75 | ITGA4 (0.46) | MAPTALDH1A1PTGS2LMNAMEN1 | |
| SCHEMBL13753145 | 0.75 | CNR2 (0.60) | ALDH1A1POLBMEN1KMT2ATRPA1 | |
| SCHEMBL16019870 | 0.75 | TYK2 (0.51) | MAPTPTGS2RXFP1MEN1KMT2A | |
| SCHEMBL24385583 | 0.75 | ALDH1A1 (0.59) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL8191071 | 0.75 | POLB (0.54) | MAPTALDH1A1LMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395795-B1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-07-19 | — | — | EP | disclosed |