SCHEMBL25874017

SCHEMBL25874017

CC(=O)c1ccc2nn(C)nc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.46
SLC2A1 P11166 1/20 0.42
MAPT P10636 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
POLB P06746 1/20 0.41
HCAR3 P49019 1/20 0.41
NOTUM Q6P988 1/20 0.41
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP2A6 P11509 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
NOX1 Q9Y5S8 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29750942 0.83 KDM4E (0.50) FGFR1SMN1; SMN2ALDH1A1KDM4EKMT2A
SCHEMBL2881811 0.80 KDM4E (0.51) FGFR1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL29606021 0.73 PLOD2 (0.50) MAPTPOLBHCAR3NOTUMALDH1A1
SCHEMBL12369468 0.73 HCAR3 (0.76) MAPTSMN1; SMN2NPC1RAB9APOLB
SCHEMBL6112848 0.73 ALDH1A1 (0.65) FGFR1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL29819602 0.73 ALDH1A1 (0.53) FGFR1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL28591105 0.73 MAOA (0.59) SLC2A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL21604623 0.73 MAPT (0.54) FGFR1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL16602284 0.73 ALDH1A1 (0.53) FGFR1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL12349868 0.73 HCAR3 (0.57) MAPTSMN1; SMN2NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621194-B 4-methylene-N-hydroxybenzoamide compound and application thereof 沈阳药科大学 2023-08-29 CN disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 US disclosed
CN-114621194-A 4-methylene-N-hydroxybenzamide compound and application thereof 沈阳药科大学 2022-06-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH FGFR1 1774/4885SLC2A1 2951/4885MAPT 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.