SCHEMBL25874476

SCHEMBL25874476

C=CC(=O)Oc1ccc2c(oc3c(C(F)(F)F)c(OC(=O)C=C)ccc32)c1OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.37
MAOB P27338 3/20 0.37
ALDH1A1 P00352 5/20 0.36
KDM4E B2RXH2 4/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
TYMS P04818 1/20 0.34
CYP2C9 P11712 1/20 0.33
HPGD P15428 3/20 0.33
HSD17B10 Q99714 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 1/20 0.33
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
FHIT P49789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874690 0.90 TYMS (0.39) ALDH1A1TYMSCYP2C9HPGDHSD17B10
SCHEMBL25874471 0.89 KDM4E (0.44) MAOAMAOBALDH1A1KDM4ECA12
SCHEMBL25874702 0.88 TYMS (0.34) TYMSTHRATHRB
SCHEMBL25876149 0.87 ADORA3 (0.36) MAOAMAOBALDH1A1KDM4ETYMS
SCHEMBL25876480 0.87 ADORA3 (0.34) MAOAMAOBALDH1A1TYMSCYP2C9
SCHEMBL25874544 0.87 ALDH1A1 (0.37) MAOAMAOBALDH1A1KDM4ECA12
SCHEMBL25874321 0.85 HPGD (0.39) MAOAMAOBALDH1A1KDM4ETYMS
SCHEMBL25874477 0.84 MAOA (0.40) MAOAMAOBALDH1A1KDM4ECA12
SCHEMBL25874023 0.84 TYMS (0.36) TYMS
SCHEMBL25873939 0.84 MAOA (0.41) MAOAMAOBALDH1A1KDM4ECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed