SCHEMBL25875139

SCHEMBL25875139

Cc1cn(C2CC(OC(=O)CCC(=O)O)C(C)O2)c(=O)[nH]c1=O

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.55
TK1 P04183 5/20 0.50
ABCG2 Q9UNQ0 3/20 0.47
ABCB1 P08183 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19407973 0.88 RNASE1 (0.71) RNASE1TK1
SCHEMBL3337696 0.88 RNASE1 (0.71) RNASE1TK1
SCHEMBL16417829 0.84 RNASE1 (0.49) RNASE1TK1ABCG2ABCB1
SCHEMBL17930897 0.84 RNASE1 (0.49) RNASE1TK1ABCG2ABCB1
SCHEMBL9397478 0.84 TK1 (0.65) RNASE1TK1ABCG2
SCHEMBL21078821 0.81 TOP2A (0.57) RNASE1TK1
SCHEMBL774263 0.80 RNASE1 (0.68) RNASE1TK1
SCHEMBL767324 0.80 RNASE1 (0.68) RNASE1TK1
SCHEMBL14681227 0.80 RNASE1 (0.68) RNASE1TK1
SCHEMBL16287348 0.80 RNASE1 (0.68) RNASE1TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212209-A1 COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212209-A1 COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS POLR2H, POLR2E, POLI RNASE1 333/4885TK1 325/4885ABCG2 3490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.