Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011480 | 0.82 | PKM (0.57) | PKMMAPK8MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL1317724 | 0.82 | PKM (0.53) | PKMMAPK8MAPK10IKBKBALDH1A1 | |
| SCHEMBL2593851 | 0.82 | MAPK8 (0.64) | PKMMAPK8MAPK10IKBKBALDH1A1 | |
| SCHEMBL9396711 | 0.81 | PKM (0.67) | PKMSMN1; SMN2ATMMEN1KMT2A | |
| SCHEMBL15387053 | 0.76 | MAPK8 (0.53) | PKMMAPK8MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL14295555 | 0.75 | ALDH1A1 (0.52) | PKMIKBKBALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL25876489 | 0.74 | KMT2A (0.58) | PKMMAPK8MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL6991297 | 0.74 | MAPK10 (0.51) | PKMMAPK8MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9069534 | 0.73 | L3MBTL1 (0.68) | MAPK8MAPK10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7056886 | 0.72 | PTK2 (0.70) | MAPK8MAPK10ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |