SCHEMBL25875513

SCHEMBL25875513

Cc1ccc(OC(F)(F)C(C)(F)F)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.40
L3MBTL1 Q9Y468 7/20 0.40
RAB9A P51151 5/20 0.40
ATM Q13315 1/20 0.40
ACHE P22303 1/20 0.39
HPGD P15428 4/20 0.39
MAPK1 P28482 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
ALOX12 P18054 1/20 0.39
SYK P43405 1/20 0.38
NPC1 O15118 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5755524 0.89 MAPT (0.42) MAPTL3MBTL1RAB9AATMACHE
SCHEMBL25875508 0.84 TSHR (0.39) MAPTRAB9AHPGDMAPK1NPSR1
SCHEMBL5023995 0.83 SLC1A5 (0.44) MAPTL3MBTL1RAB9AATMACHE
SCHEMBL15158671 0.83 ACHE (0.46) MAPTL3MBTL1RAB9AATMACHE
SCHEMBL25875497 0.81 ACHE (0.38) MAPTL3MBTL1RAB9AACHEHPGD
SCHEMBL25875506 0.79 ALDH1A1 (0.53) L3MBTL1RAB9AACHEALDH1A1SYK
SCHEMBL20820452 0.77 MAPT (0.49) MAPTL3MBTL1RAB9AATMACHE
SCHEMBL17815713 0.74 MAPT (0.49) MAPTL3MBTL1RAB9AATMACHE
SCHEMBL11421548 0.72 ACHE (0.52) MAPTL3MBTL1RAB9AATMACHE
SCHEMBL11910291 0.72 MAPT (0.46) MAPTL3MBTL1RAB9AATMACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed