SCHEMBL25875506

SCHEMBL25875506

Cc1ccc(OC(F)(F)C(C)(F)F)c(N)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
CYP3A4 P08684 2/20 0.53
TDP1 Q9NUW8 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALOX15 P16050 2/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42
SLC6A4 P31645 6/20 0.40
SLC6A2 P23975 5/20 0.40
SLC6A3 Q01959 5/20 0.40
HSD17B10 Q99714 1/20 0.38
CA1 P00915 1/20 0.37
ACHE P22303 1/20 0.35
SYK P43405 1/20 0.35
GAA P10253 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7934321 0.83 ALDH1A1 (0.59) ALDH1A1CYP3A4TDP1SMN1; SMN2ALOX15
SCHEMBL25875497 0.81 ACHE (0.38) ALDH1A1CYP3A4TDP1SMN1; SMN2TP53
SCHEMBL18579473 0.81 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1SMN1; SMN2ALOX15
SCHEMBL25875505 0.81 L3MBTL1 (0.34) ALDH1A1CYP3A4TDP1ALOX15THRB
SCHEMBL25875513 0.79 MAPT (0.40) ALDH1A1CYP3A4TDP1SMN1; SMN2TP53
SCHEMBL5755524 0.75 MAPT (0.42) ALDH1A1CYP3A4TDP1SMN1; SMN2TP53
SCHEMBL18579470 0.71 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1SMN1; SMN2ALOX15
Hydrochloric Acid SCHEMBL10533878 0.70 ALDH1A1 (0.59) ALDH1A1CYP3A4TDP1SMN1; SMN2ALOX15
SCHEMBL29495045 0.70 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1SMN1; SMN2ALOX15
SCHEMBL55544 0.70 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1SMN1; SMN2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed