SCHEMBL25875497

SCHEMBL25875497

Cc1ccc(OC(F)(F)C(C)(F)F)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
L3MBTL1 Q9Y468 5/20 0.37
SYK P43405 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
TP53 P04637 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
SCN10A Q9Y5Y9 1/20 0.33
GPR3 P46089 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10801181 0.82 GPR3 (0.43) ACHEL3MBTL1SYKSMN1; SMN2TP53
SCHEMBL25875513 0.81 MAPT (0.40) ACHEL3MBTL1SYKSMN1; SMN2TP53
SCHEMBL25875494 0.81 RAB9A (0.39) L3MBTL1SMN1; SMN2TP53TDP1ALDH1A1
SCHEMBL25875506 0.81 ALDH1A1 (0.53) ACHEL3MBTL1SYKSMN1; SMN2TP53
SCHEMBL12180475 0.79 ACHE (0.43) ACHEL3MBTL1SMN1; SMN2TP53TDP1
SCHEMBL25990599 0.78 ACHE (0.39) ACHEL3MBTL1SYKSMN1; SMN2TP53
SCHEMBL5755524 0.78 MAPT (0.42) ACHEL3MBTL1SYKSMN1; SMN2TP53
SCHEMBL17742255 0.76 ACHE (0.40) ACHEL3MBTL1SMN1; SMN2TP53TDP1
SCHEMBL16317278 0.76 ACHE (0.40) ACHEL3MBTL1SMN1; SMN2TP53TDP1
SCHEMBL3812564 0.76 ACHE (0.40) ACHEL3MBTL1SMN1; SMN2TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed