SCHEMBL25875514

SCHEMBL25875514

CCCCCc1cc(OC(F)(F)C(C)(F)F)ccc1Br

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.35
PPARA Q07869 3/20 0.35
TSHR P16473 2/20 0.33
CRHR1 P34998 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX5 P09917 3/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
TYR P14679 1/20 0.32
ALOX15 P16050 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
HPSE Q9Y251 1/20 0.31
CNR2 P34972 2/20 0.31
HDAC1 Q13547 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875516 0.84 PPARA (0.36) PPARGPPARATSHRMEN1KMT2A
SCHEMBL2873180 0.72 MGLL (0.40) TSHRMEN1KMT2AALDH1A1ALOX5
SCHEMBL27480325 0.72 ERBB2 (0.44) HDAC1
SCHEMBL25875499 0.72 HAO1 (0.40) TSHRMEN1KMT2AALDH1A1MAPT
SCHEMBL13324440 0.71 LTA4H (0.51) PPARGPPARATSHRKMT2AALDH1A1
SCHEMBL18908923 0.69 GPR3 (0.41) TSHRCRHR1ALDH1A1PTGS2
SCHEMBL9388053 0.69 TYR (0.34) TSHRMEN1KMT2AALDH1A1TYR
SCHEMBL27574849 0.69 TYR (0.44) TSHRMEN1KMT2AALDH1A1ALOX5
SCHEMBL14850388 0.69 S1PR1 (0.40) PPARGPPARATSHRMEN1KMT2A
SCHEMBL2292266 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed