SCHEMBL25875516

SCHEMBL25875516

CCCCCc1cc(OC(F)(F)C(C)(F)F)ccc1C

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.36
PPARG P37231 3/20 0.36
TSHR P16473 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX5 P09917 2/20 0.33
TYR P14679 2/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
CHRM5 P08912 1/20 0.32
HPSE Q9Y251 1/20 0.32
CNR2 P34972 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875514 0.84 PPARG (0.35) PPARAPPARGTSHRMEN1KMT2A
SCHEMBL23153214 0.77 PTGS2 (0.44) ALOX5TDP1
SCHEMBL14583346 0.75 CNR2 (0.50) TSHRMEN1KMT2AALDH1A1TP53
SCHEMBL25875503 0.74 TDP1 (0.38) MEN1KMT2AALDH1A1MAPTHTT
SCHEMBL13659 0.71 KCNH2 (0.37) TP53CYP3A4MAPTALOX15CHRM5
SCHEMBL5859441 0.71 LIPG (0.45) TSHRMEN1KMT2AALDH1A1ALOX5
SCHEMBL14355888 0.71 MGLL (0.40) TSHRMEN1KMT2AALDH1A1ALOX5
SCHEMBL5858851 0.71 LIPG (0.45) TSHRMEN1KMT2AALDH1A1ALOX5
SCHEMBL9770516 0.70 TYR (0.41) TSHRMEN1KMT2AALDH1A1ALOX5
SCHEMBL11942564 0.70 ALOX5 (0.44) TSHRMEN1KMT2AALOX5TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed