SCHEMBL25875523

SCHEMBL25875523

CC(F)(F)C(F)(F)OCCc1ccc(Br)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.40
HTR2A P28223 1/20 0.39
PPARD Q03181 2/20 0.37
PPARA Q07869 2/20 0.37
IDO1 P14902 2/20 0.34
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
GLA P06280 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875524 0.90 TAAR1 (0.38) TAAR1HTR2APPARDPPARAIDO1
SCHEMBL25875519 0.81 IDO1 (0.45) TAAR1IDO1MAOAMAOBKDM4E
SCHEMBL24213899 0.81 TAAR1 (0.45) TAAR1HTR2APPARDPPARAIDO1
SCHEMBL25875525 0.74 KCNH2 (0.42) TAAR1KDM4ECTDSP1
SCHEMBL28128016 0.71 TAAR1 (0.47) TAAR1HTR2AIDO1POLBCTDSP1
SCHEMBL4263497 0.70 TAAR1 (0.42) TAAR1HTR2APPARDPPARAIDO1
SCHEMBL26988119 0.70 TAAR1 (0.42) TAAR1HTR2APPARDPPARAIDO1
SCHEMBL517859 0.70 TAAR1 (0.50) TAAR1HTR2AIDO1MAOAMAOB
SCHEMBL2515837 0.69 TAAR1 (0.54) TAAR1HTR2AIDO1MAOAMAOB
SCHEMBL2719969 0.68 CYP4F2 (0.46) HTR2APPARDPPARAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed