SCHEMBL25875525

SCHEMBL25875525

Cc1ccc(CCCOC(F)(F)C(C)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.42
DRD2 P14416 1/20 0.39
DRD4 P21917 1/20 0.39
DRD3 P35462 1/20 0.39
IGF1R P08069 1/20 0.39
ALOX15 P16050 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
EDNRB P24530 1/20 0.37
EDNRA P25101 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
HRH1 P35367 1/20 0.36
MAPT P10636 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875524 0.85 TAAR1 (0.38) TAAR1CTDSP1KDM4ENPC1RAB9A
SCHEMBL25875521 0.78 AGXT (0.47) KCNH2CYP1A2CYP2A6TAAR1NPC1
SCHEMBL25875523 0.74 TAAR1 (0.40) TAAR1CTDSP1KDM4E
SCHEMBL171910 0.71 KCNH2 (0.50) KCNH2DRD2DRD4DRD3IGF1R
SCHEMBL4589012 0.70 CYP1A2 (0.46) KCNH2DRD2DRD4DRD3IGF1R
SCHEMBL14498996 0.70 CYP1A2 (0.46) KCNH2DRD2DRD4DRD3IGF1R
SCHEMBL3481944 0.70 KCNH2 (0.49) KCNH2DRD2DRD4DRD3IGF1R
SCHEMBL21185863 0.70 KCNH2 (0.62) KCNH2DRD2DRD4DRD3SMN1; SMN2
SCHEMBL6546878 0.70 CYP1A2 (0.62) KCNH2DRD2DRD4DRD3IGF1R
SCHEMBL6546754 0.70 IGF1R (0.64) KCNH2DRD2DRD4DRD3IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed