SCHEMBL25875524

SCHEMBL25875524

CC(F)(F)C(F)(F)OCCCc1ccc(Br)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.38
HTR2A P28223 1/20 0.37
SIGMAR1 Q99720 1/20 0.34
PPARD Q03181 2/20 0.33
PPARA Q07869 2/20 0.33
NPC1 O15118 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HMOX1 P09601 1/20 0.33
IDO1 P14902 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875523 0.90 TAAR1 (0.40) TAAR1HTR2APPARDPPARAL3MBTL1
SCHEMBL25875525 0.85 KCNH2 (0.42) TAAR1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL4263497 0.82 TAAR1 (0.42) TAAR1HTR2ASIGMAR1PPARDPPARA
SCHEMBL25875519 0.79 IDO1 (0.45) TAAR1NPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL4858 0.72 TAAR1 (0.47) TAAR1HTR2ASIGMAR1NPC1NFKB1
SCHEMBL28893555 0.72 TAAR1 (0.50) TAAR1HTR2ASIGMAR1HMOX1IDO1
SCHEMBL9717244 0.72 TAAR1 (0.42) TAAR1HTR2ASIGMAR1NPC1NFKB1
SCHEMBL24213899 0.71 TAAR1 (0.45) TAAR1HTR2APPARDPPARAIDO1
SCHEMBL410888 0.70 DUT (0.40) TAAR1HTR2ASIGMAR1PPARDPPARA
SCHEMBL2130427 0.69 RAB9A (0.49) TAAR1HTR2ASIGMAR1NPC1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed