Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310959 | 0.86 | RAB9A (0.64) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL29466342 | 0.86 | RAB9A (0.64) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL25876087 | 0.83 | MEN1 (0.60) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL25312498 | 0.81 | MAPT (0.53) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL25884809 | 0.80 | NPC1 (0.50) | KDM4EMEN1KMT2ARAB9ATDP1 | |
| SCHEMBL25876099 | 0.79 | MEN1 (0.55) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL25876445 | 0.79 | RAB9A (0.55) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL25883121 | 0.79 | RAB9A (0.55) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL25879067 | 0.79 | KMT2A (0.55) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL15408966 | 0.79 | KDM4E (0.54) | KDM4EMEN1KMT2ARAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |