Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | RHOA | P61586 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310959 | 1.00 | RAB9A (0.64) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25876087 | 0.86 | MEN1 (0.60) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25876316 | 0.86 | MAPT (0.60) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25883121 | 0.82 | RAB9A (0.55) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25876445 | 0.82 | RAB9A (0.55) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25879067 | 0.82 | KMT2A (0.55) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25876099 | 0.82 | MEN1 (0.55) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25881254 | 0.81 | LMNA (0.56) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25312498 | 0.80 | MAPT (0.53) | RAB9AKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL18286208 | 0.80 | AURKA (0.60) | RAB9AKDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057932-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-03-24 | — | — | WO | disclosed |
| WO-2022057928-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-03-24 | — | — | WO | disclosed |
| CN-114195780-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195806-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |