Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25882621 | 0.91 | KMT2A (0.49) | KMT2AMAPTMEN1KDM4EALPG | |
| SCHEMBL25882618 | 0.86 | BCHE (0.45) | KMT2AMAPTMEN1KDM4EALPG | |
| SCHEMBL25310959 | 0.82 | RAB9A (0.64) | KMT2AMAPTMEN1KDM4EALPG | |
| SCHEMBL29466342 | 0.82 | RAB9A (0.64) | KMT2AMAPTMEN1KDM4EALPG | |
| SCHEMBL25876087 | 0.79 | MEN1 (0.60) | KMT2AMAPTMEN1KDM4EALPG | |
| SCHEMBL25876316 | 0.79 | MAPT (0.60) | KMT2AMAPTMEN1KDM4EALPG | |
| SCHEMBL25311803 | 0.76 | MAPT (0.45) | KMT2AMAPTMEN1KDM4EALPG | |
| SCHEMBL25311797 | 0.76 | MAPT (0.45) | KMT2AMAPTMEN1KDM4EALPG | |
| SCHEMBL25879066 | 0.76 | GSK3A (0.57) | KMT2AMAPTRAB9A | |
| SCHEMBL7341190 | 0.76 | RAB9A (0.47) | KMT2AMAPTMEN1KDM4EALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |