Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 5/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466342 | 0.82 | RAB9A (0.64) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL25310959 | 0.82 | RAB9A (0.64) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL25876316 | 0.79 | MAPT (0.60) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL25876087 | 0.79 | MEN1 (0.60) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL25879067 | 0.75 | KMT2A (0.55) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL25876445 | 0.75 | RAB9A (0.55) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL25876099 | 0.75 | MEN1 (0.55) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL25312498 | 0.74 | MAPT (0.53) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL3759875 | 0.73 | MAPT (1.00) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL25884697 | 0.72 | MAPT (0.55) | RAB9AMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |