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SCHEMBL2587651

SCHEMBL2587651

Nc1ccc(/N=N/c2ccccc2)c2ccc(S(=O)(=O)O)cc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2C9 P11712 1/20 0.73
▸ CYP2C19 P33261 1/20 0.73
▸ HSD17B10 Q99714 1/20 0.73
▸ SENP2 Q9HC62 6/20 0.72
▸ SENP1 Q9P0U3 6/20 0.72
▸ SENP3 Q9H4L4 5/20 0.72
▸ SUMO2 P61956 4/20 0.72
▸ SUMO1 P63165 4/20 0.72
▸ SENP7 Q9BQF6 4/20 0.72
▸ PHLPP2 Q6ZVD8 1/20 0.72
▸ MEN1 O00255 3/20 0.59
▸ KMT2A Q03164 3/20 0.59
▸ TDP1 Q9NUW8 2/20 0.59
▸ NPC1 O15118 1/20 0.59
▸ MAPT P10636 1/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ GLO1 Q04760 5/20 0.56
▸ SLC7A11 Q9UPY5 1/20 0.54
▸ POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2587653 1.00 CYP2C9 (0.73) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL15274121 0.99 SENP2 (0.74) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL12177946 0.99 CYP2C9 (0.72) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL15274123 0.95 SENP2 (0.77) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL15120312 0.95 SENP2 (0.72) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL12177898 0.93 CYP2C9 (0.76) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL2585430 0.92 CYP2C9 (0.81) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL2585427 0.92 CYP2C9 (0.81) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL15274174 0.92 CYP2C9 (0.67) CYP2C9CYP2C19HSD17B10SENP2SENP1
SCHEMBL12177914 0.91 SENP3 (0.88) CYP2C9CYP2C19HSD17B10SENP2SENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9573887-B2 Naphthalene derivative DAITO CHEMIX CORPORATION (JP) 2017-02-21 — — US disclosed
US-9573887-B2 Naphthalene derivative DAITO CHEMIX CORPORATION (JP) 2017-02-21 — — US disclosed
EP-2566941-B1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2016-12-21 — — EP disclosed
EP-2599771-B1 NAPHTHALENE DERIVATIVE DAITO CHEMIX CORP (JP) 2016-09-14 — — EP disclosed
US-8585780-B2 Dyes and blends for shading during laundry BASF SE (DE) 2013-11-19 — — US disclosed
US-20130247309-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2013-09-26 — — US disclosed
US-20130184241-A1 Naphthalene Derivative KYOTO UNIVERSITY (JP) 2013-07-18 — — US disclosed
US-20130184241-A1 Naphthalene Derivative KYOTO UNIVERSITY (JP) 2013-07-18 — — US disclosed
EP-2566941-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2013-03-13 — — EP disclosed
WO-2011138183-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2011-11-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130184241-A1 Naphthalene Derivative VCP, NOC2L, VAT1 CYP2C9 841/4885CYP2C19 892/4885HSD17B10 477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.