Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17629885 | 0.88 | MAPT (0.36) | LTA4HMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18871951 | 0.86 | DPP4 (0.36) | TOP2ATOP2BMAPTNPC1RAB9A | |
| SCHEMBL18839910 | 0.84 | LTA4H (0.44) | LTA4HMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18871725 | 0.84 | ALDH1A1 (0.47) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18871724 | 0.84 | ALDH1A1 (0.34) | PPARGMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17629968 | 0.83 | BTK (0.37) | PPARGPPARAMAPTNPC1RAB9A | |
| SCHEMBL18871723 | 0.83 | ALDH1A1 (0.36) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18839941 | 0.83 | SRD5A2 (0.44) | TTRMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL22470187 | 0.81 | ACHE (0.34) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18839885 | 0.81 | CYP19A1 (0.38) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713314-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | ENI S.P.A. (IT) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713314-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | SCO2, NR3C2, CBR3 | LTA4H 4344/4885TOP2A 2850/4885TOP2B 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.