Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17629885 | 0.91 | MAPT (0.36) | BTKKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL18839910 | 0.86 | LTA4H (0.44) | KDM4EMAPTALDH1A1KMT2ACYP3A4 | |
| SCHEMBL18871725 | 0.86 | ALDH1A1 (0.47) | BTKKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL18871724 | 0.86 | ALDH1A1 (0.34) | BTKKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL22470187 | 0.83 | ACHE (0.34) | BTKKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL18839885 | 0.83 | CYP19A1 (0.38) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL25877127 | 0.83 | LTA4H (0.48) | BTKKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL18839941 | 0.83 | SRD5A2 (0.44) | KDM4EMAPTALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL18871723 | 0.83 | ALDH1A1 (0.36) | BTKKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL18839881 | 0.83 | SRPK1 (0.42) | KDM4EMAPTALDH1A1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11706979-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | ENI S.P.A. (IT) | 2023-07-18 | — | — | US | disclosed |
| US-11706979-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | ENI S.P.A. (IT) | 2023-07-18 | — | — | US | disclosed |
| US-11706979-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | ENI S.P.A. (IT) | 2023-07-18 | — | — | US | disclosed |
| US-20210408393-A1 | Disubstituted Diaryloxybenzoheterodiazole Compounds | ENI S.P.A. (IT) | 2021-12-30 | — | — | US | disclosed |
| US-20210408393-A1 | Disubstituted Diaryloxybenzoheterodiazole Compounds | ENI S.P.A. (IT) | 2021-12-30 | — | — | US | disclosed |
| US-11133474-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | ENI S.P.A. (IT) | 2021-09-28 | — | — | US | disclosed |
| US-11133474-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | ENI S.P.A. (IT) | 2021-09-28 | — | — | US | disclosed |
| US-20170250350-A1 | Disubstituted Diaryloxybenzoheterodiazole Compounds | ENI S.P.A. (IT) | 2017-08-31 | — | — | US | disclosed |
| US-20170250350-A1 | Disubstituted Diaryloxybenzoheterodiazole Compounds | ENI S.P.A. (IT) | 2017-08-31 | — | — | US | disclosed |
| US-20170250350-A1 | Disubstituted Diaryloxybenzoheterodiazole Compounds | ENI S.P.A. (IT) | 2017-08-31 | — | — | US | disclosed |
| EP-3197890-A1 | DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS | ENI S.p.A. (IT) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046319-A1 | DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS | ENI S.P.A. (IT) | 2016-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210408393-A1 | Disubstituted Diaryloxybenzoheterodiazole Compounds | SCLY, NR2E3, CDK15 | BTK 845/4885KDM4E 2677/4885MAPT 4192/4885 |
| US-11133474-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | SCLY, C1S, SLC39A3 | BTK 1227/4885KDM4E 3210/4885MAPT 4554/4885 |
| US-11706979-B2 | Disubstituted diaryloxybenzoheterodiazole compounds | SCLY, NR2E3, CDK15 | BTK 845/4885KDM4E 2677/4885MAPT 4192/4885 |
| US-20170250350-A1 | Disubstituted Diaryloxybenzoheterodiazole Compounds | SCLY, C1S, SLC39A3 | BTK 1227/4885KDM4E 3210/4885MAPT 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.