Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539265 | 0.85 | ALDH1A1 (0.51) | CYP3A4SMN1; SMN2TDP1ADORA3ALDH1A1 | |
| SCHEMBL3544064 | 0.84 | CYP3A4 (0.45) | CYP3A4SMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3542442 | 0.83 | CYP3A4 (0.44) | CYP3A4SMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL4791455 | 0.81 | CYP3A4 (0.42) | CYP3A4SMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3540275 | 0.81 | CYP3A4 (0.42) | CYP3A4SMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3538236 | 0.81 | CYP3A4 (0.42) | CYP3A4SMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL7361832 | 0.80 | SMN1; SMN2 (0.50) | CYP3A4SMN1; SMN2TDP1ADORA3ALDH1A1 | |
| SCHEMBL3539018 | 0.80 | CYP3A4 (0.41) | CYP3A4SMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL7358402 | 0.79 | CYP3A4 (0.49) | CYP3A4SMN1; SMN2TDP1ADORA3ALDH1A1 | |
| SCHEMBL14967024 | 0.78 | ALDH1A1 (0.44) | CYP3A4SMN1; SMN2TDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219973-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219973-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | USP7, USP28, USP1 | CYP3A4 4130/4885SMN1; SMN2 2139/4885TDP1 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.