SCHEMBL25878435

SCHEMBL25878435

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc(-c4cccc(-c5cc6c(cc5-c5ccc7oc8ccccc8c7c5)-c5ccccc5C65C6CC7CC(C6)CC5C7)c4)cc3)n2)cc1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPT P10636 3/20 0.32
HPGD P15428 3/20 0.32
KMT2A Q03164 3/20 0.32
KDM4E B2RXH2 2/20 0.31
LMNA P02545 2/20 0.31
GLA P06280 1/20 0.31
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31
PLA2G10 O15496 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25878419 0.90 PLA2G2A (0.31) PLA2G2APLA2G4APLA2G10
SCHEMBL23606115 0.89 PLA2G2A (0.34) ALDH1A1MAPTHPGDKDM4ELMNA
SCHEMBL25878426 0.89 PLA2G10 (0.31) PLA2G2APLA2G4APLA2G10
SCHEMBL24608719 0.89 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10
SCHEMBL24608695 0.88 PLA2G2A (0.32) ALDH1A1MAPTHPGDKDM4EPLA2G2A
SCHEMBL23606119 0.88 PLA2G2A (0.34) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL23605940 0.87 HTT (0.33) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL25878391 0.86 PLA2G2A (0.36) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL24608808 0.86 PLA2G2A (0.32) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL23605770 0.86 ALDH1A1 (0.33) MEN1ALDH1A1MAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM MEN1 2884/4885ALDH1A1 213/4885MAPT 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.