SCHEMBL25878359

SCHEMBL25878359

c1ccc(-c2ccc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccc6c(c5)C5(c7cc(-c8cccc9c8oc8ccccc89)ccc7-6)C6CC7CC(C6)CC5C7)n4)c3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
PRKDC P78527 7/20 0.35
GGPS1 O95749 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.33
TSHR P16473 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
AVPR1A P37288 1/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
MAPT P10636 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23605936 0.92 ALOX5 (0.37) ALOX5PRKDCGGPS1TSHRMEN1
SCHEMBL25035871 0.91 ALOX5 (0.38) ALOX5PRKDCGGPS1PTGES2TSHR
SCHEMBL25817529 0.90 ALOX5 (0.34) ALOX5PRKDCTSHRMEN1KMT2A
SCHEMBL24618527 0.89 HTT (0.33) TSHRMEN1KMT2AKDM4EALDH1A1
SCHEMBL25817644 0.89 HTT (0.31) ALOX5TSHRMEN1KMT2AKDM4E
SCHEMBL25035861 0.89 ALOX5 (0.35) ALOX5PRKDCGGPS1TSHRMEN1
SCHEMBL23605787 0.89 ALOX5 (0.39) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL25878462 0.89 ALOX5 (0.44) ALOX5PRKDCGGPS1PTGES2AVPR1A
SCHEMBL25879127 0.89 ALOX5 (0.44) ALOX5PRKDCGGPS1PTGES2AVPR1A
SCHEMBL25878391 0.88 PLA2G2A (0.36) TSHRMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ALOX5 1072/4885PRKDC 1991/4885GGPS1 526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.