Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 4/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368239 | 0.80 | CHRM2 (0.42) | KMT2AMEN1 | |
| SCHEMBL13455032 | 0.79 | ALDH1A1 (0.49) | KMT2AKLK5HDAC8MEN1 | |
| SCHEMBL646335 | 0.79 | CTSL (0.44) | KMT2ACTSLHRH2HRH1HDAC8 | |
| SCHEMBL12898931 | 0.78 | CTSK (0.38) | KMT2ACTSLKLK5CTSKCTSS | |
| SCHEMBL647656 | 0.77 | CTSS (0.46) | KMT2ACTSLHRH2HRH1HDAC8 | |
| SCHEMBL12898929 | 0.77 | CTSK (0.37) | KMT2ACTSLKLK5CTSKCTSS | |
| SCHEMBL12898928 | 0.77 | CTSK (0.37) | KMT2ACTSLKLK5HDAC8CTSK | |
| SCHEMBL14216709 | 0.76 | CTSK (0.44) | KMT2ACTSLHDAC8CTSKCA2 | |
| SCHEMBL646244 | 0.76 | MAPK1 (0.44) | KMT2ACTSLHRH2HRH1HDAC8 | |
| SCHEMBL27630344 | 0.76 | MAPK1 (0.44) | KMT2ACTSLHRH2HRH1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133336-A1 | STAT MODULATORS AND USES THEREOF | RECLUDIX PHARMA, INC. (US) | 2023-07-13 | — | — | WO | disclosed |