SCHEMBL25878525

SCHEMBL25878525

Cc1ccc2c(c1)oc1c(C(F)(F)F)c(C)ccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
GAA P10253 2/20 0.40
HPGD P15428 2/20 0.40
MAOB P27338 2/20 0.37
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CDC25A P30304 1/20 0.35
CDC25C P30307 1/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 2/20 0.34
ELANE P08246 1/20 0.34
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP1B1 Q16678 1/20 0.33
AR P10275 1/20 0.33
KIF11 P52732 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25878374 0.82 CYP1A1 (0.33) ALDH1A1HPGDELANECYP1A1CYP1A2
SCHEMBL13563998 0.79 KIF11 (0.46) ALDH1A1GAAHPGDMAOBMAPT
SCHEMBL13563983 0.78 MAOB (0.48) ALDH1A1GAAHPGDMAOBMAPT
SCHEMBL22068539 0.78 ALDH1A1 (0.42) ALDH1A1GAAHPGDMAOBMAPT
SCHEMBL11976514 0.78 MCL1 (0.43) ALDH1A1GAAHPGDMAOBMAPT
SCHEMBL25878530 0.77 ALDH1A1 (0.37) ALDH1A1GAAHPGDMAOBMAPT
SCHEMBL16273156 0.76 AR (0.40) ALDH1A1GAAHPGDMAOBMAPT
SCHEMBL26771753 0.75 MAOB (0.40) ALDH1A1GAAHPGDMAOBMAPT
SCHEMBL25878528 0.75 ESR1 (0.33)
SCHEMBL23795525 0.73 MAOB (0.39) ALDH1A1GAAHPGDMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed