SCHEMBL25878528

SCHEMBL25878528

Cc1ccc2c(oc3c(C(F)(F)F)c(C)ccc32)c1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25878374 0.91 CYP1A1 (0.33)
SCHEMBL170628 0.84 ESR1 (0.41) ESR1ESR2
SCHEMBL18134244 0.82 CYP1A1 (0.36) ESR1ESR2
SCHEMBL25878383 0.78 MAOA (0.37) ESR1ESR2
SCHEMBL18250999 0.77 MCL1 (0.46) ESR1ESR2
SCHEMBL18134242 0.77 ESR1 (0.40) ESR1ESR2
SCHEMBL25878529 0.77
SCHEMBL18133399 0.75 ALDH1A1 (0.32) ESR1ESR2
SCHEMBL25878525 0.75 ALDH1A1 (0.40)
SCHEMBL25878532 0.75 ESR1 (0.31) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed