SCHEMBL25878374

SCHEMBL25878374

Cc1ccc2c(oc3c(C(F)(F)F)c(C)ccc32)c1C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP1B1 Q16678 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MCL1 Q07820 1/20 0.32
ELANE P08246 1/20 0.31
EPHX2 P34913 1/20 0.30
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25878528 0.91 ESR1 (0.33)
SCHEMBL25878383 0.86 MAOA (0.37) CYP1A1CYP1A2CYP1B1ALDH1A1HPGD
SCHEMBL25878529 0.85
SCHEMBL25878525 0.82 ALDH1A1 (0.40) CYP1A1CYP1A2CYP1B1ALDH1A1HPGD
SCHEMBL14423252 0.79 CYP1A2 (0.35) CYP1A2ALDH1A1HPGDHSD17B10
SCHEMBL12154091 0.75 CYP1A2 (0.33) CYP1A2ALDH1A1NOTUM
SCHEMBL25906221 0.74 ATP1A1 (0.41)
SCHEMBL26193929 0.72 CYP1A2 (0.34) CYP1A2
SCHEMBL26193931 0.71 ESR2 (0.33) CYP1A2
SCHEMBL23007612 0.71 MCL1 (0.40) CYP1A2ALDH1A1MCL1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed