Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25878638 | 0.89 | CTSV (0.42) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25665916 | 0.87 | CTSV (0.61) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25663689 | 0.87 | CTSV (0.61) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25877837 | 0.86 | CTSV (0.47) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25878725 | 0.83 | CTSV (0.42) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25878184 | 0.81 | CTSV (0.50) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25878009 | 0.77 | CTSV (0.47) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25878111 | 0.77 | CTSV (0.47) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25878044 | 0.76 | CTSV (0.51) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL25664817 | 0.74 | HTR7 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234921-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234921-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | SERPINB1, CTSV, CTSE | CTSV 2/4885CYP3A4 1869/4885CTSS 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.