Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101423 | 1.00 | MAOA (0.34) | MAOAMAOBMEN1KMT2AUSP2 | |
| SCHEMBL16534705 | 0.80 | ALDH1A1 (0.33) | MEN1KMT2AHTT | |
| SCHEMBL23187870 | 0.77 | MEN1 (0.30) | MEN1KMT2AUSP2 | |
| SCHEMBL2587972 | 0.77 | MAOA (0.46) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL7400068 | 0.73 | EGFR (0.44) | USP2HTTTSHRSMN1; SMN2 | |
| SCHEMBL21701192 | 0.72 | KMT2A (0.31) | KMT2A | |
| SCHEMBL19333348 | 0.71 | MAOA (0.38) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL18816780 | 0.71 | MAOA (0.38) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL5101353 | 0.71 | MAOA (0.38) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL6441866 | 0.71 | MAOA (0.38) | MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7692019-B2 | Methods for the stereoselective synthesis of substituted piperidines | SEPRACOR INC. (US) | 2010-04-06 | — | — | US | disclosed |
| EP-1546077-A2 | CHIRAL DIOLS, THEIR MANUFACTURE AND LIGANDS AND CATALYSTS DERIVED THEREFROM | Ciba SC Holding AG (CH) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031109-A2 | CHIRAL DIOLS, THEIR MANUFACTURE AND LIGANDS AND CATALYSTS DERIVED THEREFROM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-04-15 | — | — | WO | disclosed |