Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585816 | 0.88 | RIPK1 (0.37) | FFAR2ALDH1A1RIPK1CALCRL | |
| SCHEMBL4502251 | 0.88 | FFAR2 (0.38) | FFAR2MDM2TP53RIPK1CACNA1B | |
| SCHEMBL4502256 | 0.88 | FFAR2 (0.38) | FFAR2MDM2TP53RIPK1CACNA1B | |
| SCHEMBL3617782 | 0.88 | FFAR2 (0.35) | FFAR2MDM2TP53 | |
| SCHEMBL2583127 | 0.88 | FFAR2 (0.35) | FFAR2MDM2TP53 | |
| SCHEMBL4520271 | 0.86 | FFAR2 (0.45) | FFAR2KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4520273 | 0.86 | FFAR2 (0.45) | FFAR2KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2584668 | 0.82 | SLC6A2 (0.36) | FFAR2ALDH1A1SMN1; SMN2MDM2 | |
| SCHEMBL2584669 | 0.82 | SLC6A2 (0.36) | FFAR2ALDH1A1SMN1; SMN2MDM2 | |
| SCHEMBL2585729 | 0.82 | FFAR2 (0.35) | FFAR2RIPK1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |