SCHEMBL25880375

SCHEMBL25880375

c1ccc(-c2ccccc2-c2ccc3c4c2c2ccccc2n4c2ccc(-c4ccccc4-c4ccccc4)c4c5ccccc5n3c42)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.38
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
HTR6 P50406 2/20 0.33
MAPK14 Q16539 1/20 0.33
RET P07949 1/20 0.33
ALDH1A1 P00352 5/20 0.32
MCL1 Q07820 1/20 0.32
BAD Q92934 1/20 0.32
KDM4E B2RXH2 3/20 0.31
HPGD P15428 2/20 0.31
BRD4 O60885 1/20 0.31
MAPT P10636 1/20 0.31
PTGER1 P34995 1/20 0.31
TSHR P16473 1/20 0.31
BCL2L1 Q07817 1/20 0.31
CYP2A6 P11509 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25880354 0.91 HSD17B10 (0.41) HSD17B10HTR6MAPK14RETALDH1A1
SCHEMBL25880383 0.90 HSD17B10 (0.35) HSD17B10CRHBPCRHR2KEAP1NFE2L2
SCHEMBL25880419 0.87 MEN1 (0.34) HSD17B10RETMAPTNPC1RAB9A
SCHEMBL20857805 0.84 HSD17B10 (0.38) HSD17B10CRHBPCRHR2KEAP1NFE2L2
SCHEMBL25880402 0.82 HSD17B10 (0.37) HSD17B10ALDH1A1KDM4EHPGDMAPT
SCHEMBL25880521 0.81 KMT2A (0.37) HSD17B10RETALDH1A1KDM4EHPGD
SCHEMBL25880382 0.81 HSD17B10 (0.36) HSD17B10ALDH1A1KDM4EHPGDMAPT
SCHEMBL20857991 0.80 HSD17B10 (0.34) HSD17B10CRHBPCRHR2KEAP1NFE2L2
SCHEMBL25880394 0.80 ALDH1A1 (0.37) HSD17B10CRHBPCRHR2KEAP1NFE2L2
SCHEMBL25880355 0.80 MAPT (0.41) ALDH1A1MCL1BADKDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, NQO1 HSD17B10 1229/4885CRHBP 2044/4885CRHR2 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.