Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | LOX | P28300 | 1/20 | 0.53 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400930 | 0.85 | RECQL (0.55) | CYP2C9CYP2C19RECQLLOXLOXL3 | |
| SCHEMBL9250032 | 0.83 | RECQL (0.53) | RECQLLOXLOXL3LOXL2DYRK1A | |
| SCHEMBL30791573 | 0.83 | RECQL (0.53) | RECQLLOXLOXL3LOXL2DYRK1A | |
| SCHEMBL31286041 | 0.81 | RECQL (0.50) | CYP2C9CYP2C19RECQLNR3C2 | |
| SCHEMBL25613407 | 0.81 | GABRP (0.57) | CYP2C9CYP2C19RECQLNR3C2 | |
| SCHEMBL25610134 | 0.80 | RECQL (0.49) | CYP2C9CYP2C19RECQLCDK2GSK3B | |
| SCHEMBL5610968 | 0.77 | LOXL2 (0.58) | RECQLLOXLOXL3LOXL2EPHX1 | |
| SCHEMBL10163771 | 0.77 | L3MBTL1 (0.49) | RECQLLOXLOXL3LOXL2MAPK3 | |
| SCHEMBL31424999 | 0.76 | LOXL2 (0.57) | CYP2C9CYP2C19RECQLLOXLOXL2 | |
| SCHEMBL25880602 | 0.76 | LOX (0.57) | CYP2C9CYP2C19RECQLLOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |