Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553546 | 0.91 | NR1H2 (0.67) | NR1H2PPARGPPARDPPARAHDAC3 | |
| SCHEMBL16553538 | 0.82 | NR1H2 (0.67) | NR1H2APLNR | |
| SCHEMBL21887741 | 0.78 | NR1H2 (0.47) | NR1H2PPARGPPARDPPARAHDAC3 | |
| SCHEMBL17943738 | 0.76 | NR1H2 (0.71) | NR1H2SMPD1MALT1 | |
| SCHEMBL16553554 | 0.74 | NR1H2 (0.77) | NR1H2 | |
| SCHEMBL21887746 | 0.74 | NR1H2 (0.45) | NR1H2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17970776 | 0.73 | NR1H2 (0.71) | NR1H2SMPD1 | |
| SCHEMBL17943801 | 0.73 | NR1H2 (0.91) | NR1H2SMPD1 | |
| SCHEMBL29496569 | 0.72 | NR1H2 (0.73) | NR1H2 | |
| SCHEMBL16553563 | 0.72 | NR1H2 (0.65) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212127-A1 | LIVER X RECEPTOR (LXR) MODULATORS | ELLORA THERAPEUTICS, INC. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212127-A1 | LIVER X RECEPTOR (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PPARG 17/4885PPARD 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.