Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKCH | P24723 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 2/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945086 | 0.95 | ALDH1A1 (0.44) | ALDH1A1EPHX1CYP1A2SMN1; SMN2SPHK2 | |
| SCHEMBL2754170 | 0.93 | ALDH1A1 (0.54) | ALDH1A1EPHX1CYP1A2SMN1; SMN2SPHK2 | |
| SCHEMBL3093222 | 0.91 | ALDH1A1 (0.58) | ALDH1A1EPHX1CYP1A2SPHK2SPHK1 | |
| SCHEMBL14779416 | 0.91 | ALDH1A1 (0.58) | ALDH1A1EPHX1CYP1A2SPHK2SPHK1 | |
| SCHEMBL1666932 | 0.91 | ALDH1A1 (0.58) | ALDH1A1EPHX1CYP1A2SPHK2SPHK1 | |
| SCHEMBL14779270 | 0.91 | ALDH1A1 (0.58) | ALDH1A1EPHX1CYP1A2SPHK2SPHK1 | |
| SCHEMBL1668995 | 0.91 | ALDH1A1 (0.58) | ALDH1A1EPHX1CYP1A2SPHK2SPHK1 | |
| SCHEMBL14779341 | 0.91 | ALDH1A1 (0.58) | ALDH1A1EPHX1CYP1A2SPHK2SPHK1 | |
| SCHEMBL6896512 | 0.91 | ALDH1A1 (0.58) | ALDH1A1EPHX1CYP1A2SPHK2SPHK1 | |
| SCHEMBL25949 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130102641-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2013-04-25 | — | — | US | claimed |
| US-7790708-B2 | Prodrugs of GABA analogs, compositions and uses thereof | XENOPORT, INC. (US) | 2010-09-07 | — | — | US | claimed |
| JP-4216713-B2 | — | — | 2009-01-28 | — | — | JP | claimed |
| EP-1902714-A1 | Prodrugs of gaba analogs, compositions and uses thereof | Xenoport, Inc. (US) | 2008-03-26 | — | — | EP | claimed |
| EP-1404324-B1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT INC (US) | 2007-12-05 | — | — | EP | claimed |
| US-7060727-B2 | Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2006-06-13 | — | — | US | claimed |
| EP-1404324-A4 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT INC (US) | 2004-12-22 | — | — | EP | claimed |
| JP-2004536873-A | — | — | 2004-12-09 | — | — | JP | claimed |
| US-20040147455-A1 | Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof | XENOPORT, INC. | 2004-07-29 | — | — | US | claimed |
| WO-2004052360-A1 | PRODRUGS OF FUSED GABA ANALOGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2004-06-24 | — | — | WO | claimed |
| EP-1404324-A2 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | Xenoport, Inc. (US) | 2004-04-07 | — | — | EP | claimed |
| US-20030176398-A1 | Prodrugs of GABA analogs, compositions and uses thereof | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2003-09-18 | — | — | US | claimed |
| WO-2002100347-A2 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2002-12-19 | — | — | WO | claimed |
| CN-113557327-B | Polyacetal fiber, method for producing same, and material for drawing | 三菱瓦斯化学株式会社 | 2022-06-28 | — | — | CN | disclosed |
| EP-3116509-B1 | A NEW CLASS OF MU-OPIOID RECEPTOR AGONISTS | UNIV COLUMBIA (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-113557327-A | Polyacetal fiber, method for producing same, and material for drawing | 三菱瓦斯化学株式会社 | 2021-10-26 | — | — | CN | disclosed |
| US-5744676-A | DIMERIZATION, CATALYSTS | AMOCO CORPORATION | 1998-04-28 | — | — | US | disclosed |
| EP-0039029-B1 | USE OF SUBSTITUTED 2-(1-METHYLBUTYL)-1,3-DIOXANES AS PERFUMING AGENTS AND PERFUME COMPOSITIONS CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1984-07-04 | — | — | EP | disclosed |
| EP-0039029-A2 | Use of substituted 2-(1-methylbutyl)-1,3-dioxanes as perfuming agents and perfume compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-11-04 | — | — | EP | disclosed |
| US-4104247-A | PROPYLENE HOMO- OR COPOLYMERS ALUMINIC ESTERS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102641-A1 | PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF | GABRB1, GABRB2, GABRB3 | ALDH1A1 298/4885EPHX1 846/4885CYP1A2 135/4885 |
| US-20030176398-A1 | Prodrugs of GABA analogs, compositions and uses thereof | GABRB1, GABRB2, GABRB3 | ALDH1A1 298/4885EPHX1 846/4885CYP1A2 135/4885 |
| US-20040147455-A1 | Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof | GABRB1, GABRB2, GABRB3 | ALDH1A1 380/4885EPHX1 1218/4885CYP1A2 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.