SCHEMBL258865

SCHEMBL258865

S=c1[nH]c2ccccc2n1-c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 2/20 0.68
PDE7B Q9NP56 2/20 0.68
ALDH1A1 P00352 8/20 0.68
HPGD P15428 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
MAPT P10636 2/20 0.68
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
APOBEC3G Q9HC16 2/20 0.56
MPI P34949 1/20 0.56
RXFP1 Q9HBX9 2/20 0.55
PSMB8 P28062 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.50
HTT P42858 1/20 0.50
KDM4E B2RXH2 3/20 0.48
ATM Q13315 2/20 0.48
RECQL P46063 1/20 0.46
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299573 0.81 PDE7A (1.00) PDE7APDE7BALDH1A1HPGDSMN1; SMN2
SCHEMBL30193439 0.81 PDE7A (1.00) PDE7APDE7BALDH1A1HPGDSMN1; SMN2
SCHEMBL4931051 0.79 PSMB8 (0.57) PDE7APDE7BALDH1A1HPGDSMN1; SMN2
SCHEMBL17437483 0.79 PDE7A (0.53) PDE7APDE7BALDH1A1HPGDSMN1; SMN2
SCHEMBL30103233 0.78 PDE7A (1.00) PDE7APDE7BALDH1A1HPGDSMN1; SMN2
SCHEMBL844588 0.78 PDE7A (1.00) PDE7APDE7BALDH1A1HPGDSMN1; SMN2
SCHEMBL15206647 0.78 PDE7A (0.57) PDE7APDE7BALDH1A1HPGDSMN1; SMN2
SCHEMBL699273 0.76 LMNA (0.65) PDE7APDE7BALDH1A1HPGDMAPT
SCHEMBL29367625 0.76 LMNA (0.65) PDE7APDE7BALDH1A1HPGDMAPT
SCHEMBL30910102 0.73 PDE7A (0.51) PDE7APDE7BALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119789670-A Perovskite solar cell and preparation method thereof 中建科工集团有限公司 2025-04-08 CN claimed
CN-122055426-A Sealing member 住友理工株式会社 2026-05-15 CN disclosed
US-20260015469-A1 HEAT-RESISTANT SILANE CROSSLINKED RESIN FORMED BODY, SILANE CROSSLINKABLE RESIN COMPOSITION, METHOD OF PRODUCING SAME, AND WIRING MATERIAL FURUKAWA ELECTRIC CO., LTD. (JP) 2026-01-15 US disclosed
US-20250230308-A1 POLYMER COMPOSITION ENEOS MATERIALS CORPORATION (JP) 2025-07-17 US disclosed
CN-119789670-A Perovskite solar cell and preparation method thereof 中建科工集团有限公司 2025-04-08 CN disclosed
EP-3831857-B1 RESIN COMPOSITION ENEOS MAT CORPORATION (JP) 2025-03-12 EP disclosed
EP-4464741-A1 POLYMER COMPOSITION ENEOS Materials Corporation (JP) 2024-11-20 EP disclosed
WO-2024195048-A1 HEAT-RESISTANT SILANE-CROSSLINKED RESIN MOLDED ARTICLE, SILANE-CROSSLINKABLE RESIN COMPOSITION, METHODS FOR PRODUCING SAME, AND WIRING MATERIAL 古河電気工業株式会社 2024-09-26 WO disclosed
CN-118541435-A Polymer composition 株式会社引能仕材料 2024-08-23 CN disclosed
US-11952483-B2 Resin composition ENEOS CORPORATION (JP) 2024-04-09 US disclosed
EP-2513107-A1 HETEROAROMATIC PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS H. Lundbeck A/S (DK) 2012-10-24 EP disclosed
EP-2472319-A2 Titanium black dispersion composition, black radiation-sensitive composition containing the same, black cured film, solid state imaging element and method for producing a black cured film Fujifilm Corporation (JP) 2012-07-04 EP disclosed
US-20120135987-A1 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS H. LUNDBECK A/S (DK) 2012-05-31 US disclosed
US-8133897-B2 Phenylimidazole derivatives as PDE10A enzyme inhibitors H. LUNDBECK A/S (DK) 2012-03-13 US disclosed
WO-2012007006-A1 TRIAZOLO- AND PYRAZOLOQUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITOR H. LUNDBECK A/S (DK) 2012-01-19 WO disclosed
WO-2011072696-A1 2-ARYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS H. LUNDBECK A/S (DK) 2011-06-23 WO disclosed
WO-2011072694-A1 HETEROAROMATIC PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS H. LUNDBECK A/S (DK) 2011-06-23 WO disclosed
EP-2318394-A1 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS H. Lundbeck A/S (DK) 2011-05-11 EP disclosed
US-20100016303-A1 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS H. LUNDBECK A/S (DK) 2010-01-21 US disclosed
WO-2009152825-A1 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS H. LUNDBECK A/S (DK) 2009-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015469-A1 HEAT-RESISTANT SILANE CROSSLINKED RESIN FORMED BODY, SILANE CROSSLINKABLE RESIN COMPOSITION, METHOD OF PRODUCING SAME, AND WIRING MATERIAL SEM1, PCNA, RPL34 PDE7A 4771/4885PDE7B 4870/4885ALDH1A1 330/4885
US-20100016303-A1 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS PDE10A, PDE5A, PDE3B PDE7A 10/4885PDE7B 13/4885ALDH1A1 65/4885
US-20120135987-A1 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS PDE10A, PDE5A, PDE3B PDE7A 10/4885PDE7B 13/4885ALDH1A1 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.