Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150851 | 1.00 | PDE7A (0.51) | PDE7APDE7BALDH1A1ADORA3PARP1 | |
| SCHEMBL26089069 | 0.86 | ADORA3 (0.48) | ALDH1A1ADORA3PARP1TSHRCASP1 | |
| SCHEMBL30910123 | 0.86 | ADORA3 (0.48) | ALDH1A1ADORA3PARP1TSHRCASP1 | |
| SCHEMBL7103857 | 0.82 | GRIN2D (0.47) | ALDH1A1PARP1TSHRCASP1GRIA1 | |
| SCHEMBL29367625 | 0.81 | LMNA (0.65) | PDE7APDE7BALDH1A1L3MBTL1KDM4E | |
| SCHEMBL699273 | 0.81 | LMNA (0.65) | PDE7APDE7BALDH1A1L3MBTL1KDM4E | |
| SCHEMBL26088643 | 0.80 | OPRM1 (0.48) | ALDH1A1ADORA3MPIOPRM1OPRL1 | |
| SCHEMBL30910121 | 0.80 | OPRM1 (0.48) | ALDH1A1ADORA3MPIOPRM1OPRL1 | |
| SCHEMBL5500479 | 0.80 | JAK2 (0.52) | PDE7APDE7BALDH1A1ADORA3PARP1 | |
| SCHEMBL7782299 | 0.78 | PDE7A (0.45) | PDE7APDE7BALDH1A1ADORA3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | disclosed |