SCHEMBL2588809

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12175984	0.92	CNR2 (0.36)	CNR2MTNR1AMTNR1BKDM4EGAA
	SCHEMBL2462830	0.87	PTGS2 (0.38)	MTNR1AMTNR1BKDM4EGAASMN1; SMN2
	SCHEMBL12175993	0.87	POLB (0.38)	KDM4ESMN1; SMN2TP53MMP13HPGD
	SCHEMBL2461285	0.86	PTGS2 (0.40)	CNR2KDM4EGAASMN1; SMN2PTGS2
	SCHEMBL12175914	0.86	CD274 (0.47)	CNR2KDM4EGAAMMP13HPGD
	SCHEMBL12160578	0.83	GYS1 (0.39)	KDM4EGAAPTGS2HPGDHSD17B10
	SCHEMBL2492254	0.81	MAOB (0.37)	MTNR1AMTNR1BGAAPTGS2
	SCHEMBL1136167	0.80	MAOB (0.39)	GAAPTGS2
	SCHEMBL2581569	0.80	KDM4E (0.34)	MTNR1AMTNR1BKDM4EGAARAB9A
	SCHEMBL1136308	0.79	MAOB (0.39)	GAAPTGS2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.