SCHEMBL25890393

SCHEMBL25890393

CC(C)(C)OC(=O)NC1(C(=O)Nc2cncc(C(F)F)c2)CC1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.41
GHSR Q92847 1/20 0.39
BDKRB1 P46663 4/20 0.39
FAAH O00519 8/20 0.35
TRPV1 Q8NER1 5/20 0.33
NAMPT P43490 2/20 0.33
CYP17A1 P05093 1/20 0.32
APLNR P35414 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31654381 1.00 FPR2 (0.41) FPR2GHSRBDKRB1FAAHTRPV1
SCHEMBL31654157 0.84 FPR2 (0.54) FPR2GHSRBDKRB1FAAHNAMPT
SCHEMBL2825969 0.83 NAMPT (0.45) NAMPTCYP17A1APLNR
SCHEMBL31654583 0.83 FAAH (0.44) FPR2GHSRBDKRB1FAAHTRPV1
SCHEMBL25890389 0.83 FAAH (0.44) FPR2GHSRBDKRB1FAAHTRPV1
SCHEMBL31654116 0.82 FAAH (0.42) FPR2GHSRBDKRB1FAAHTRPV1
SCHEMBL25890390 0.82 FAAH (0.42) FPR2GHSRBDKRB1FAAHTRPV1
SCHEMBL25890392 0.78 GHSR (0.43) FPR2GHSRBDKRB1FAAHTRPV1
SCHEMBL31611248 0.77 NAMPT (0.57) FPR2GHSRNAMPT
SCHEMBL26318454 0.77 NAMPT (0.57) FPR2GHSRNAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed