SCHEMBL25890392

SCHEMBL25890392

CC(C)(C)OC(=O)NC1(C(=O)Nc2ccc(C(F)F)nc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.43
FPR2 P25090 2/20 0.40
FAAH O00519 6/20 0.39
BDKRB1 P46663 4/20 0.39
TRPV1 Q8NER1 4/20 0.37
PSMB8 P28062 1/20 0.35
NAMPT P43490 1/20 0.35
AAK1 Q2M2I8 2/20 0.35
CYP17A1 P05093 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25890301 0.84 FPR2 (0.56) GHSRFPR2FAAHBDKRB1TRPV1
SCHEMBL1421040 0.83 NAMPT (0.48) PSMB8NAMPTCYP17A1
SCHEMBL25890219 0.83 GHSR (0.44) GHSRFPR2FAAHBDKRB1TRPV1
SCHEMBL25890386 0.82 ALDH1A1 (0.47) GHSR
SCHEMBL25890393 0.78 FPR2 (0.41) GHSRFPR2FAAHBDKRB1TRPV1
SCHEMBL31654381 0.78 FPR2 (0.41) GHSRFPR2FAAHBDKRB1TRPV1
SCHEMBL19033765 0.77 GHSR (0.53) GHSRFAAHTRPV1PSMB8CYP17A1
SCHEMBL31611248 0.77 NAMPT (0.57) GHSRFPR2NAMPT
SCHEMBL26318454 0.77 NAMPT (0.57) GHSRFPR2NAMPT
SCHEMBL6235125 0.76 FAAH (0.56) GHSRFPR2FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A GHSR 608/4885FPR2 2179/4885FAAH 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.