SCHEMBL25890662

SCHEMBL25890662

CC(C)(C)Cn1nnc2c1-c1ccccc1C(=O)N(C(C)(C)C)c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 12/20 0.38
IDO1 P14902 11/20 0.38
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CES1 P23141 2/20 0.31
TTR P02766 1/20 0.31
POLB P06746 1/20 0.31
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25890747 0.95 TDO2 (0.38) TDO2IDO1SMN1; SMN2HPGDMAPK1
SCHEMBL25895953 0.83 TDO2 (0.39) TDO2IDO1SMN1; SMN2HPGDMAPK1
SCHEMBL23869690 0.82 IDO1 (0.33) TDO2IDO1SMN1; SMN2CES1TTR
SCHEMBL25895952 0.81 TOP2A (0.43) TDO2IDO1SMN1; SMN2HPGDMAPK1
SCHEMBL25892503 0.78 SMN1; SMN2 (0.31) SMN1; SMN2HTTPOLB
SCHEMBL23869733 0.77 IDO1 (0.33) TDO2IDO1SMN1; SMN2CES1TTR
SCHEMBL24479357 0.72 IDO1 (0.30) TDO2IDO1
SCHEMBL20151895 0.72 ALDH1A1 (0.44) TDO2IDO1SMN1; SMN2HPGDMAPK1
SCHEMBL16980287 0.71 CHRM2 (0.34) TDO2IDO1ALDH1A1CES1BCHE
SCHEMBL18272795 0.71 TTR (0.49) TDO2IDO1HPGDALDH1A1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235082-A1 SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) 2023-07-27 US disclosed
US-20230235082-A1 SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235082-A1 SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME FUT5, FUT6, SIGLEC7 TDO2 1135/4885IDO1 177/4885SMN1; SMN2 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.