Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | P4HA1 | P13674 | 3/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070876 | 0.82 | P4HA1 (0.55) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL14822487 | 0.80 | P4HA1 (0.53) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL25804618 | 0.79 | P4HA1 (0.52) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL15718539 | 0.79 | P4HA1 (0.52) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL600427 | 0.79 | P4HA1 (0.52) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL30521254 | 0.79 | P4HA1 (0.52) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL28970323 | 0.76 | P4HA1 (0.57) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL7108880 | 0.75 | NAPRT (0.49) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL29534992 | 0.75 | P4HA1 (0.47) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL29418677 | 0.74 | L3MBTL1 (0.57) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227429-A1 | SULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227429-A1 | SULPHONAMIDE COMPOUNDS | MLKL, RIPK3, CASP1 | ALDH1A1 4663/4885CYP1A2 4017/4885CYP2C9 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.