SCHEMBL25891133

SCHEMBL25891133

Cc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O[C@H]3OC(Cn4cc(C(C)(C)C)nn4)[C@@H](O)[C@H](O)C3O)[C@H](O)C2O)c(=O)[nH]1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FUT5 Q11128 1/20 0.55
P2RX3 P56373 1/20 0.52
TGM2 P21980 1/20 0.51
IMPDH2 P12268 5/20 0.50
IMPDH1 P20839 1/20 0.50
P2RY6 Q15077 5/20 0.49
KRAS P01116 2/20 0.49
TAS1R3 Q7RTX0 1/20 0.48
TAS1R1 Q7RTX1 1/20 0.48
P2RY2 P41231 4/20 0.48
P2RY4 P51582 4/20 0.48
NT5E P21589 1/20 0.47
P2RY1 P47900 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25898915 0.94 FUT5 (0.64) FUT5P2RX3TGM2P2RY6KRAS
SCHEMBL25891136 0.94 FUT5 (0.64) FUT5P2RX3TGM2P2RY6KRAS
SCHEMBL25898913 0.94 FUT5 (0.64) FUT5P2RX3TGM2P2RY6KRAS
SCHEMBL25891108 0.87 FUT5 (0.62) FUT5P2RX3TGM2IMPDH2IMPDH1
SCHEMBL25891116 0.86 FUT5 (0.60) FUT5P2RX3TGM2IMPDH2IMPDH1
SCHEMBL25890762 0.84 FUT5 (0.58) FUT5P2RX3TGM2IMPDH2IMPDH1
SCHEMBL25890760 0.83 FUT5 (0.59) FUT5P2RX3TGM2IMPDH2IMPDH1
SCHEMBL18269536 0.81 P2RX3 (0.68) FUT5P2RX3TGM2IMPDH2IMPDH1
SCHEMBL18289612 0.81 P2RX3 (0.68) FUT5P2RX3TGM2IMPDH2IMPDH1
SCHEMBL18158963 0.81 P2RX3 (0.68) FUT5P2RX3TGM2IMPDH2IMPDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235082-A1 SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME GLYCO-THERAPY BIOTECHNOLOGY CO., LTD. (CN) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235082-A1 SITE-SPECIFIC ANTIBODY CONJUGATES AND THE METHODS FOR PREPARATION OF THE SAME FUT5, FUT6, SIGLEC7 FUT5 1/4885P2RX3 4839/4885TGM2 179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.