Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472192 | 0.89 | SLC10A2 (0.33) | SLC10A2ALDH1A1KDM4E | |
| SCHEMBL7470085 | 0.89 | SLC10A2 (0.33) | SLC10A2ALDH1A1KDM4E | |
| SCHEMBL19170232 | 0.84 | CDK4 (0.32) | SLC10A2 | |
| SCHEMBL2589094 | 0.83 | MAOA (0.37) | NPSR1KDM4E | |
| SCHEMBL2585237 | 0.82 | MAPK1 (0.32) | MAPT | |
| SCHEMBL17506155 | 0.81 | DRD2 (0.32) | SLC10A2 | |
| SCHEMBL17506154 | 0.81 | DRD2 (0.32) | SLC10A2 | |
| SCHEMBL7469254 | 0.81 | EGFR (0.40) | SLC10A2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7463854 | 0.81 | EGFR (0.40) | SLC10A2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL2589896 | 0.80 | MAPK1 (0.35) | SLC10A2FGFR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563122-A1 | CHEMICAL COMPOUNDS | Glaxosmithkline LLC (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011137135-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-11-03 | — | — | WO | disclosed |