Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | YWHAG | P61981 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 2/20 | 0.42 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200551 | 0.94 | PPARA (0.44) | PPARAPPARGYWHAGNPC1PKM | |
| SCHEMBL6553321 | 0.88 | ALDH1A1 (0.50) | YWHAGNPC1PKMNFKB1RAB9A | |
| SCHEMBL8201063 | 0.86 | ALDH1A1 (0.51) | YWHAGNPC1PKMNFKB1RAB9A | |
| SCHEMBL2587585 | 0.86 | SELP (0.47) | PPARAPPARGNPC1PKMNFKB1 | |
| SCHEMBL8709712 | 0.83 | ALDH1A1 (0.48) | NPC1PKMNFKB1RAB9ANFKB2 | |
| SCHEMBL8710187 | 0.83 | PPARA (0.52) | PPARAPPARGSELPSELPLG | |
| SCHEMBL8205873 | 0.82 | PPARA (0.44) | PPARAPPARGNPC1PKMNFKB1 | |
| SCHEMBL27559039 | 0.79 | FAAH (0.53) | SMN1; SMN2CYP4F2CYP4A11THRATHRB | |
| SCHEMBL2589668 | 0.78 | PTPN11 (0.41) | PPARAPPARGNPC1PKMNFKB1 | |
| SCHEMBL1630566 | 0.78 | PPARA (0.65) | PPARAPPARGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566580-A1 | PROCESS FOR THE PREPARATION OF BIMOSIAMOSE | Revotar Biopharmaceuticals AG (DE) | 2013-03-13 | — | — | EP | claimed |
| WO-2011138365-A1 | PROCESS FOR THE PREPARATION OF BIMOSIAMOSE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2011-11-10 | — | — | WO | claimed |
| CN-103002951-A | Process for the preparation of new compound | REVOTAR BIOPHARMACEUTICALS AG | 2013-03-27 | — | — | CN | disclosed |
| EP-2566580-A1 | PROCESS FOR THE PREPARATION OF BIMOSIAMOSE | Revotar Biopharmaceuticals AG (DE) | 2013-03-13 | — | — | EP | disclosed |
| EP-2566580-A1 | PROCESS FOR THE PREPARATION OF BIMOSIAMOSE | Revotar Biopharmaceuticals AG (DE) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138365-A1 | PROCESS FOR THE PREPARATION OF BIMOSIAMOSE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011138365-A1 | PROCESS FOR THE PREPARATION OF BIMOSIAMOSE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2011-11-10 | — | — | WO | disclosed |
| EP-0840606-B1 | DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS | TEXAS BIOTECHNOLOGY CORP (US) | 2000-06-07 | — | — | EP | disclosed |
| US-5919768-A | COMPOUNDS WHICH INHIBIT BINDING OF SELECTINS TO SIALYL-LEWIS-X AND SIALYL-LEWIS-A CARBOHYDRATES | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |